The function tests the gene association with trait conditional
on isoforms
Usage
conditional_test(w_gene, w_iso, ld, z, gene_name, tx_name)
Arguments
- w_gene
vector, weights for gene
- w_iso
matrix, weights for significant isoforms
- ld
matrix, LD matrix
- z
vector, GWAS Z-scores
- gene_name
character, gene name
- tx_name
vector, character vector of tx names in order of columns of Y
Value
data frame of conditional Z-scores for all combinations of tx