computeTME.RdThe function takes in a SNP-mediator set-gene triplet and computes the total mediation effect with boots structure
computeTME(snp, expression, mediators, covs, indices)
| snp | vector, SNP of interest |
|---|---|
| expression | vector, gene expression of interest |
| mediators | data frame, mediators of interest |
| covs | data frame, covariates |
| indices | blank, index for boot package |
estimate of TME